10222-62-5

Basic information

• Product Name: 2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID
• Synonyms: TIMTEC-BB SBB011041;AKOS BB-6925;2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID;Albb-005461;2-methoxyquinoline-4-carboxylic acid(SALTDATA: FREE);2-methoxy-4-quinolinecarboxylic acid;2-methoxycinchoninic acid;4-Quinolinecarboxylic acid, 2-methoxy-
• CAS NO: 10222-62-5
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19
• Mol File: 10222-62-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 359.6°C at 760 mmHg
• Flash Point: 171.3°C
• Appearance: /
• Density: 1.325g/cm³
• Vapor Pressure: 8.51E-06mmHg at 25°C
• Refractive Index: 1.648
• PKA: 1.05±0.10(Predicted)
• CAS DataBase Reference: 2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID(10222-62-5)
• EPA Substance Registry System: 2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID(10222-62-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 10222-62-5(Hazardous Substances Data)

Usage

General Description

2-Methoxy-quinoline-4-carboxylic acid is a chemical compound with the molecular formula C11H9NO4. It is a derivative of quinoline and contains a carboxylic acid functional group and a methoxy group. 2-METHOXY-QUINOLINE-4-CARBOXYLIC ACID is commonly used as a building block in the synthesis of various pharmaceuticals and organic compounds. It has also been studied for its potential anti-inflammatory and antioxidant properties. Additionally, 2-methoxy-quinoline-4-carboxylic acid has shown promising activity against certain bacteria and fungi, making it a potential candidate for the development of new antibacterial and antifungal agents. It is important to handle this compound with care, as it may pose health hazards if not handled properly.

InChI:InChI=1/C11H9NO3/c1-15-10-6-8(11(13)14)7-4-2-3-5-9(7)12-10/h2-6H,1H3,(H,13,14)

Upstream product

• 124-41-4 sodium methylate 
• 115801-85-9 2-methoxy-quinoline-4-carboxylic acid methyl ester 

Downstream Products

• 1312556-94-7 (S)-2-methoxy-N-methyl-N-(4-(1-methyl-1H-pyrrole-2-carboxamido)-1-phenylbutan-2-yl)quinoline-4-carboxamide 

Relevant articles and documents

QUINOLINE DERIVATIVE HAVING SEROTONIN-3 RECEPTOR ANTAGONIZING ACTIVITY

Quinoline derivatives represented by formula (I): STR1 wherein A-B-D represents--C(COO--Y)=CH--C(OR)= (wherein Y represents 8-methyl-8-azabicyclo[3.2.1]oct-3-yl group and R represents alkyl) or--C(OH)=C(COX--Y)--CH= (wherein X represents--O--or--NH--; and Y has the same meaning as described above), or a pharmaceutically acceptable salt thereof, possess potent 5HT 3 antagonizing activity and are useful as antiemetic agents.

QUINOLINE SUBSTITUTED OXOMETHYL OR THIOXOMETHYL GLYCINE DERIVATIVES AND ALDOSE REDUCTASE INHIBITON THEREWITH

A compound of the formula (I): or a pharmaceutically acceptable salt thereof, wherein Y is S or O; R is hydrogen or alkyl having from about 1 to about 4carbon atoms; R1 is hydrogen, alkyl having from about 1 to about 4carbon atoms, alkoxy having from about 1 to about 4carbon atoms, halogen or trifluoromethyl; R2 is hydrogen or unsubstituted or substituted alkyl having from about 1 to about 4 carbon atoms; and R3 is hydrogen, alkyl having from about 1 to about 6carbon atoms, cycloalkyl having from about 3 to about 6 carbon atoms, alkoxy having from about 1 to about 4 carbon atoms, aryloxy having from about 6 to about 10 carbon atoms, alkylthio having from about 1 to about 4 carbon atoms, hydroxyalkoxy having from about 1 to about 4 carbon atoms, or unsubstituted or substituted phenyl is useful to obtain inhibition of aldose reduction in animals, including humans.