1022282-86-5Relevant academic research and scientific papers
Reaction of 1-tert-butyl-3,4-diphenyl-1,2,4-triazol-5-ylidenes with a malonic ester
Korotkikh, Nikolai I.,Cowley, Alan H.,Moore, Jennifer A.,Glinyanaya, Nataliya V.,Panov, Ilia S.,Rayenko, Gennady F.,Pekhtereva, Tatyana M.,Shvaika, Oles P.
, p. 195 - 199 (2008/09/20)
Four stable carbenes, 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d, including new fluorine-containing compounds 1c,d, react with a malonic ester to afford heterocyclic zwitterionic compounds 5a-d. The reactions with more acidic compounds (ethyl acetoacetate, malononitrile and 1,3-dimethylbarbituric acid) proceed with substrate deprotonation to form the respective azolium salts 6a-c. The X-ray crystal structure of 5a was also determined. The Royal Society of Chemistry 2008.
