102236-53-3

Basic information

• Product Name: Ethyl 3-broMo-4,5-diMethyl-1H-pyrrole-2-carboxylate
• Synonyms: Ethyl 3-broMo-4,5-diMethyl-1H-pyrrole-2-carboxylate;3-Bromo-4,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester
• CAS NO: 102236-53-3
• Molecular Formula: C₉H₁₂BrNO₂
• Molecular Weight: 246.10108
• Mol File: 102236-53-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 3-broMo-4,5-diMethyl-1H-pyrrole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 3-broMo-4,5-diMethyl-1H-pyrrole-2-carboxylate(102236-53-3)
• EPA Substance Registry System: Ethyl 3-broMo-4,5-diMethyl-1H-pyrrole-2-carboxylate(102236-53-3)

Safety Data

• Hazardous Substances Data: 102236-53-3(Hazardous Substances Data)

Upstream product

• 2199-45-3 4,5-dimethyl-pyrrole-2-carboxylic acid ethyl ester 
• 600-31-7 2-bromomalonic acid 

Relevant articles and documents

Efficient synthesis of an A-B-C-tricycle fragment for a structural model of tolyporphin

An efficient stereocontrolled synthesis of an A-B-C-tricycle fragment 7 for a structural model of tolyporphin 3 is described. All the rings were prepared from readily available starting materials. One of the two key steps is a selective ring-opening reaction of the lactone cycle in bicyclolactam-lactone 17 to cyanopyrrolidone 18, which introduces the chirality into synthetic compounds. The other key step is the combination of A ring with B-C-bicycle via a two-time Eschenmoser sulfide contraction. A-B-C-tricycle fragment 7 allows a new approach toward tolypophin compounds and other uroporphinoids.