102252-80-2

Upstream product

• 102253-02-1 6-<2-(dimethylamino)ethenyl>-5-(4-nitrobenzoyl)-2(1H)-pyridinone 
• 102252-95-9 3-amino-1-(4-nitrophenyl)-2-buten-1-one 
• 4023-82-9 4-nitrobenzoylacetone 
• 102267-48-1 5-(4-nitrophenyl)-1,6-naphthyridin-2(1H)-one 
• 55130-67-1 6-methyl-5-(4-nitrobenzoyl)-2(1H)-pyridinone 

Relevant academic research and scientific papers

Novel cAMP PDE III Inhibitors: 1,6-Naphthyridin-2(1H)-ones

Two series of medorinone (3) analogs were prepared by modifications at C(2) and C(5).The C(2)-series was prepared from 2-chloro-5-methyl-1,6-naphthyridine (4) by replacement of the chloro group with various nucleophiles.The C(5)-series was prepared from 5

5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation

1-R-5-Ar-1,6-naphthyridin-2(1H)-ones (I) or salts thereof, where R is hydrogen or methyl, and Ar is phenyl or phenyl substituted by methyl, ethyl, methoxy, ethoxy, hydroxy, amino, acetylamino, methanesulfonylamino, bromo, chloro, fluoro, cyano or carbamyl