1022600-91-4

Basic information

• Product Name: 11-(TERT-BUTYL)SPIRO[1,2,3-TRIHYDROQUINAZOLINE-2,4'-CYCLOHEXANE]-4-ONE
• Synonyms: 11-(TERT-BUTYL)SPIRO[1,2,3-TRIHYDROQUINAZOLINE-2,4'-CYCLOHEXANE]-4-ONE;4-tert-butyl-3',4'-dihydro-1'H-spiro[cyclohexane-1,2'-quinazoline]-4'-one;Spiro[cyclohexane-1,2'(1'H)-quinazolin]-4'(3'H)-one, 4-(1,1-dimethylethyl)-
• CAS NO: 1022600-91-4
• Molecular Formula: C17H24N2O
• Molecular Weight: 272.39
• Mol File: 1022600-91-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 274-276 °C(Solv: acetone (67-64-1))
• Boiling Point: 482.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• PKA: 15.77±0.40(Predicted)
• CAS DataBase Reference: 11-(TERT-BUTYL)SPIRO[1,2,3-TRIHYDROQUINAZOLINE-2,4'-CYCLOHEXANE]-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 11-(TERT-BUTYL)SPIRO[1,2,3-TRIHYDROQUINAZOLINE-2,4'-CYCLOHEXANE]-4-ONE(1022600-91-4)
• EPA Substance Registry System: 11-(TERT-BUTYL)SPIRO[1,2,3-TRIHYDROQUINAZOLINE-2,4'-CYCLOHEXANE]-4-ONE(1022600-91-4)

Safety Data

• Hazardous Substances Data: 1022600-91-4(Hazardous Substances Data)

Upstream product

• 98-53-3 4-tercbutyl-cyclohexanone 
• 28144-70-9 anthranilic acid amide 

Relevant articles and documents

Click reaction: Highly efficient synthesis of 2,3-dihydroquinazolin-4(1H)- ones

In this work, condensation reaction of 2-aminobenzamide with various alkyl, aryl, and alicyclic aldehydes or ketones to 2,3-dihydroquinazolin-4(1H)-one derivatives in the presence of a catalytic amount of ammonium chloride in ethanol at room temperature is described. This reaction can be classified as a click chemical synthesis because of its high yields, short reaction times, and green and efficient reaction medium. Copyright Taylor & Francis Group, LLC.