102262-55-5

Basic information

• Product Name: N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine
• Synonyms: N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine;N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-imino-2-phenazinamine
• CAS NO: 102262-55-5
• Molecular Formula: C₂₄H₁₆Cl₂N₄
• Molecular Weight: 431.31664
• Mol File: 102262-55-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine(102262-55-5)
• EPA Substance Registry System: N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine(102262-55-5)

Safety Data

• Hazardous Substances Data: 102262-55-5(Hazardous Substances Data)

Usage

Description

N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine is a phenazine derivative, characterized by its dark purple solid appearance and solubility in organic solvents. This chemical compound has garnered interest due to its potential applications in medicine, material science, and the textile industry, attributed to its anti-bacterial, anti-cancer, antioxidant, and anti-inflammatory properties.

Uses

Used in Pharmaceutical Applications:
N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine is used as a pharmaceutical agent for its anti-bacterial and anti-cancer properties. It has been studied for its potential to combat various types of bacteria and cancer cells, making it a promising candidate for further research and development in the medical field.
Used in Material Science:
In the field of material science, N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine is utilized for its potential applications in the development of new materials with unique properties. Its chemical structure and properties may contribute to the creation of innovative materials with enhanced performance characteristics.
Used in Textile Industry:
N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine is used as a dye in the textile industry, capitalizing on its dark purple color. Its use in this industry can lead to the production of vibrant and long-lasting colored textiles, enhancing the aesthetic appeal and durability of fabrics.
Used in Antioxidant and Anti-inflammatory Applications:
Due to its antioxidant and anti-inflammatory properties, N,5-bis(4-chlorophenyl)-3-iMino-3,5-dihydrophenazin-2-aMine is employed in various applications that require these characteristics. It can be used in the development of pharmaceuticals, cosmetics, and other products that benefit from its ability to reduce oxidative stress and inflammation.

Upstream product

• 68817-71-0 2-(4-chloroanilino)aniline 
• 1332634-91-9 N¹-(4-chlorophenyl)-N²-(5-fluoro-2,4-dinitrophenyl)benzene-1,2-diamine 
• 327-92-4 1,5-difluoro-2,4-dinitrobenzene 

Downstream Products

• 106691-11-6 [1,4-Dichloro-5-(4-chloro-phenyl)-3-imino-3,5-dihydro-phenazin-2-yl]-(2,4-dichloro-phenyl)-amine 
• 106690-90-8 3-(2-bromo-4-chloroanilino)-10-(4-chlorophenyl)-1,4-dibromo-2,10-dihydro-2-iminophenazine 
• 2030-63-9 clofazimine 
• 106691-07-0 3-(2-bromo-4-chloroanilino)-10-(4-chlorophenyl)-2-cyclohexylimino-2,10-dihydrophenazine 
• 106691-06-9 1-bromo-3-(2-bromo-4-chloroanilino)-10-(4-chlorophenyl)-2,10-dihydro-2-iminophenazine 

Relevant articles and documents

Clofazimine derivatives as potent broad-spectrum antiviral agents with dual-target mechanism

Thirty-two clofazimine derivatives, of which twenty-two were new, were synthesized and evaluated for their antiviral effects against both rabies virus and pseudo-typed SARS-CoV-2, taking clofazimine (1) as the lead. Among them, compound 15f bearing 4-methoxy-2-pyridyl at the N5-position showed superior or comparable antiviral activities to lead 1, with the EC50 values of 1.45 μM and 14.6 μM and the SI values of 223 and 6.1, respectively. Compound 15f inhibited rabies and SARS-CoV-2 by targeting G or S protein to block membrane fusion, as well as binding to L protein or nsp13 to inhibit intracellular biosynthesis respectively, and thus synergistically exerted a broad-spectrum antiviral effect. The results provided useful scientific data for the development of clofazimine derivatives into a new class of broad-spectrum antiviral candidates.