Cas 1022955-49-2,N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide

1022955-49-2

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Product Name: N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide
Synonyms: N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide
CAS NO:1022955-49-2
Molecular Formula:
Molecular Weight: 567.152
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
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Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide(CAS DataBase Reference)
NIST Chemistry Reference: N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide(1022955-49-2)
EPA Substance Registry System: N-((1R,2R)-2-{5-chloro-2-[8-methoxy-3-(2-methoxyethyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino]pyrimidin-4-ylamino}cyclohexyl)-N-methyl-methanesulfonamide(1022955-49-2)

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Hazardous Substances Data: 1022955-49-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1022955-49-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,2,9,5 and 5 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1022955-49:
(9*1)+(8*0)+(7*2)+(6*2)+(5*9)+(4*5)+(3*5)+(2*4)+(1*9)=132
132 % 10 = 2
So 1022955-49-2 is a valid CAS Registry Number.

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1022955-49-2Relevant academic research and scientific papers

Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors

Zificsak, Craig A.,Theroff, Jay P.,Aimone, Lisa D.,Angeles, Thelma S.,Albom, Mark S.,Cheng, Mangeng,Mesaros, Eugen F.,Ott, Gregory R.,Quail, Matthew R.,Underiner, Ted L.,Wan, Weihua,Dorsey, Bruce D.

, p. 3877 - 3880 (2011/08/06)

The incorporation of R,R-1,2-diaminocyclohexane at C4 in a series of 2,4-diaminopyrimidines led to a number of ALK inhibitors in which optimized activity was achieved by conversion of the 2-amino group into a methanesulfonamide. Tumor growth inhibition wa

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