10233-24-6

Basic information

• Product Name: TRIETHYLENE GLYCOL MONOSTEARATE
• Synonyms: 2,2'-ETHYLENEDIOXYDIETHANOL MONOSTEARATE;2,2'-ETHYLENEDIOXYETHANOL MONOSTEARATE;GLYCOL BIS(HYDROXYETHYL)ETHER MONOSTEARATE;ETHYLENE GLYCOL DIHYDROXYDIETHYL ETHER MONOSTEARATE;DI-B-HYDROXYETHOXYETHANE MONOSTEARATE;TRIETHYLENE GLYCOL MONOSTEARATE;TRIGLYCOL MONOSTEARATE;2-[2-(2-hydroxyethoxy)ethoxy]ethyl stearate
• CAS NO: 10233-24-6
• Molecular Formula: C₂₄H₄₈O₅
• Molecular Weight: 416.63
• EINECS: 233-562-2
• Mol File: 10233-24-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 508.1°Cat760mmHg
• Flash Point: 155.5°C
• Appearance: /
• Density: 0.95g/cm³
• Vapor Pressure: 1.89E-12mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: TRIETHYLENE GLYCOL MONOSTEARATE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIETHYLENE GLYCOL MONOSTEARATE(10233-24-6)
• EPA Substance Registry System: TRIETHYLENE GLYCOL MONOSTEARATE(10233-24-6)

Safety Data

• Hazardous Substances Data: 10233-24-6(Hazardous Substances Data)

Usage

General Description

Triethylene glycol monostearate, also known as TEGMS, is a chemical compound that is commonly used as an emulsifier and surfactant in various industrial applications. It is a non-ionic substance that is made by the esterification of stearic acid with triethylene glycol. TEGMS is often utilized in the production of personal care products, cosmetics, and pharmaceuticals as a stabilizer and thickening agent. It also finds use in food production as a food additive and in the manufacturing of plastics, polymers, and lubricants. Additionally, TEGMS is employed in the petroleum industry as an additive in drilling fluids and lubricants. Overall, TEGMS serves as a versatile and multifunctional chemical with a wide range of industrial applications.

InChI:InChI=1/C24H48O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(26)29-23-22-28-21-20-27-19-18-25/h25H,2-23H2,1H3

Relevant articles and documents

Combinatorial synthesis of PEG oligomer libraries

A simple chain-extending approach was established for the scale-up of the monoprotected monodisperse PEG diol materials. Reactions of THP-(OCH2CH2)n—OMs (n=4, 8, 12) with a large excess of commercially available H—(OCH2CH2)n—OH (n=1-4) under basic conditions led to THP-(OCH2CH2)n—OH (n=5-15). Similarly, Me-(OCH2CH2)n—OH (n=4-11, 13) were prepared from Me-(OCH2CH2)n—OMs (n=3, 7, 11). For the chain elongation steps, 40-80% yields were achieved through extraction purification. PEG oligomer libraries I and II were generated in 50-95% overall yields by alkylation or acylation of THP-(OCH2CH2)n—OH (n=1-15) followed by deprotection. Alkylation of Me-(OCH2CH2)n—OH (n=1-11, 13) with X—(CH2)m—CO2R (X=Br or OMs) and subsequent hydrolysis led to PEG oligomer library III in 30-60% overall yields. Combinatorial purification techniques were adapted to the larger-scale library synthesis. A total of 498 compounds, each with a weight of 2-5 g and a minimum purity of 90%, were synthesized.