10234-72-7

Basic information

• Product Name: 3-Pyrazolidinone
• Synonyms: 3-Oxopyrazolidine; 3-Pyrazolidone
• CAS NO: 10234-72-7
• Molecular Formula: C₃H₆N₂O
• Molecular Weight: 86.0925
• Mol File: 10234-72-7.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.114g/cm³
• CAS DataBase Reference: 3-Pyrazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrazolidinone(10234-72-7)
• EPA Substance Registry System: 3-Pyrazolidinone(10234-72-7)

Safety Data

• Hazardous Substances Data: 10234-72-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Pyrazolidinone is used as a key building block for the synthesis of various pharmaceuticals due to its versatile chemical structure and potential to be modified into novel bioactive compounds. Its anticonvulsant and sedative properties make it particularly valuable for the development of drugs targeting neurological disorders.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Pyrazolidinone serves as a crucial intermediate in the synthesis of agrochemicals, contributing to the development of new products that can enhance crop protection and management.
Used in Dye and Pigment Production:
3-Pyrazolidinone is used as a key intermediate in the production of dyes and pigments, where its chemical properties allow for the creation of a wide range of colorants for various applications in industries such as textiles, plastics, and printing inks.
Used in Industrial Chemicals:
3-Pyrazolidinone also finds application in the synthesis of other industrial chemicals, leveraging its chemical versatility to contribute to the development of new materials and products across different sectors.

Upstream product

• 17822-51-4 1-benzylidene-3-oxo-1-pyrazolidinium-2-ide 
• 60-34-4 methylhydrazine 
• 103-26-4 methyl cinnamate 

Downstream Products

• 1258237-28-3 (Z)-2-(2-methoxybenzylidene)-5-oxopyrazolidin-2-ium-1-ide 
• 909095-78-9 1-{5-[2-(2,6-dichlorophenyl)-3-oxoethyl]-2-methylsulfanylpyrimidin-4-yl}pyrazolidin-3-one 
• 130064-95-8 1-(o-Nitrobenzyl)pyrazolidin-3-one 
• 69624-88-0 C₁₀H₉BrN₂O 
• 1427577-07-8 2-(3,5-dimethoxybenzylidene)-5-oxopyrazolidin-2-ium-1-ide 

Relevant articles and documents

Detection hydrazine florescent probe of fluorescein matrix structure

The invention provides a detection hydrazine florescent probe of a fluorescein matrix structure and relates to the field of fluorescent probes. The detection hydrazine florescent probe is prepared bythe following steps: S1, adding proper amounts of dichlorofluorescein and triethylamine into a round-bottom flask; S2, adding a proper amount of anhydrous dichloroethane, performing mixing and stirring, slowly adding dropwise a proper amount of an anhydrous dichloroethane solution into which acryloyl chloride is dissolved into the round-bottom flask, performing a reaction at the room temperature,and performing TLC (thin-layer chromatography) monitoring; and S3, after the reaction is completed, relieving the vacuum state, performing spinning drying on a solvent, and performing column chromatography, so as to obtain the probe. Through a reaction of hydrazine with a probe molecule substrate by virtue of an intensive nucleophilic property of the hydrazine, a dichloro fluorophore matrix is released, the fluorescence develops from zero, and furthermore, detection research on hydrazine can be achieved.

Methylaluminoxane (MAO)-assisted direct amidation of esters

Aliphatic and aromatic esters are efficiently transformed into amides in good to excellent yields, under mild conditions using methylaluminoxane (MAO). This reaction can be performed either at room temperature or by applying microwave irradiation.

Combinatorial libraries of substrate-bound cyclic organic compounds

The invention relates to libraries of cyclic organic compounds and method of producing and assaying such libraries. According to the invention, each cyclic organic compound is constructed from a starting material in the form of a solid surface derivatized with a starting resin. Compounds are reacted with the resin to add or to form a cyclic group. The reactions are preferable carried out using a split resin procedure so that different compounds can be reacted with a plurality of subamounts so as to increase the size of the library. For example, compounds are reacted with a solid support bound starting resin to obtain a compound which includes an aldehyde functional group wherein the aldehyde compound or compounds reacted with it have substituents which are varied such that a mixture of products is obtained. The invention further relates to methods of producing combinatorial libraries of cyclic organic compounds from substrate bound compounds by cleaving the compounds from the support after synthesizing is completed and to assaying libraries of such compounds.

ADDITION-ADDITION-ELIMINATION MECHANISM OF 1,3-DIPOLE "DIMERIZATION"

Proof is presented for the three step ADD-ADD-EL pathway to thermal "dimers" of pyrazolidin-3-one-azomethinimines without a centre of symmetry, pyrazolidin-3-one acting as a special type of nucleophilic catalyst.