102354-00-7Relevant articles and documents
Iminoformylation Reaction of Substituted Crotonnitriles. I. Synthesis of New N,N-Disubstituted 4-Amino-1,1-dicyanobuta-1,3-dienes
Koeckritz, P.,Sattler, R.,Liebscher, J.
, p. 567 - 579 (2007/10/02)
A usefull and efficient method for the synthesis of 4-amino-1,1-dicyanobuta-1,3-dienes 10-20 based on the iminoformylation reaction of crotonnitriles 7-9 with the system triethyl orthoformate/secondary amine in the presence of an acidic catalyst is described.This novel route to the title compounds yields products which are easy to isolate and to purify and also allows to prepare the hitherto unknown N-aryl substituted 4-amino-1,1-dicyanobuta-1,3-dienes.Hence it is advantageous as compared to existing iminoformylation reactions of crotonnitriles using formamide acetals.
