102361-94-4

Basic information

• Product Name: Benzoyl chloride, 4-cyano-2-methoxy- (9CI)
• Synonyms: Benzoyl chloride, 4-cyano-2-methoxy- (9CI)
• CAS NO: 102361-94-4
• Molecular Formula: C₉H₆ClNO₂
• Molecular Weight: 195.60244
• Product Categories: ACIDHALIDE
• Mol File: 102361-94-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 338.8±32.0 °C(Predicted)
• Appearance: /
• Density: 1.32±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzoyl chloride, 4-cyano-2-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 4-cyano-2-methoxy- (9CI)(102361-94-4)
• EPA Substance Registry System: Benzoyl chloride, 4-cyano-2-methoxy- (9CI)(102361-94-4)

Safety Data

• Hazardous Substances Data: 102361-94-4(Hazardous Substances Data)

Upstream product

• 79-37-8 oxalyl dichloride 
• 89469-52-3 2-methoxy-4-cyano-benzoic acid 
• 2486-80-8 4-amino-2-methoxybenzoic acid 

Downstream Products

• 89454-64-8 2-(4-Carbamoyl-2-methoxyphenyl)-1H-imidazo<4,5-b>pyridine hydrochloride 
• 89454-61-5 2-(4-Cyano-2-methoxyphenyl)-1H-imidazo<4,5-b>pyridine hydrochloride 
• 108288-31-9 2-(4-cyano-2-methoxyphenyl)-1H-imidazo<4,5-c>pyridine monohydrochloride 
• 108288-29-5 3-Methoxy-4-(5-methyl-5H-imidazo[4,5-c]pyridin-2-yl)-benzonitrile 
• 108288-28-4 2-(4-cyano-2-hydroxyphenyl)-5-methylimidazo<4,5-c>pyridine 
• 108288-26-2 N-(3-Amino-pyridin-4-yl)-4-cyano-2-methoxy-benzamide 
• 102361-56-8 2-(4-carbamoyl-2-methoxyphenyl)imidazo<1,2-a>pyrimidine 
• 143489-48-9 2-(4-cyano-2-methoxyphenyl)imidazo<1,2-a>pyrimidine 
• 102361-96-6 2-bromo-4'-cyano-2'-methoxyacetophenone 
• 14221-78-4 4'-cyano-2'-methoxyacetophenone 
• 316810-05-6 N-(2-amino-4,5-dichlorophenyl)-2-methoxy-4-cyanobenzamide 

Relevant articles and documents

Glycosyl ortho-Methoxybenzoates: Catalytically Activated Glycosyl Donors with an Easily Removable and Recyclable Leaving Group

We describe the β-ortho-methoxybenzoate as a shelf stable and practical C-1 nucleofuge for catalytic chemical glycosylation in which the benzoic acid by-product can be easily removed, reisolated, and potentially recycled after the glycosylation reaction. This new type of glycosyl donor can be efficiently activated by a range of promoters, including Bi(OTf)3, Fe(OTf)3, TMSOTf (TMS = trimethylsilyl), and triflic acid, with low (10 mol-%) catalyst loadings. The donor shows higher reactivity than analogous benzoate, p-methoxybenzoate and p-cyano-o-methoxybenzoate donors. In glycosylation reactions with o-methoxybenzoate donors, the yields of disaccharide products were good to excellent for various glycosyl acceptors, including a carbohydrate-based secondary alcohol. Furthermore, β-selective mannosylation was achieved with a Crich-type donor at 0 °C to ambient temperature, without donor preactivation. The donor was also used for the first step of a one-pot two-step glycosylation to obtain a trisaccharide; the second coupling involved activation of a thioglycoside with NIS/TMSOTf (NIS = N-iodosuccinimide). We believe that this offers a good alternative to current protocols.

Piperazine based inhibitors of factor xa

Novel compounds of the general formulae (I) or (II), including their pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa are described. Compositions containing such compounds a

Inotropic 2-arylimidazo[1,2-a]pyrimidines

A series of 2-arylimidazo[1,2-a]pyrimidines has been prepared and evaluated for inotropic activity. Three of these heterocycles, ether 19, sulphide 21 and mesylate 24 displayed more potent inotropic effects in vitro than isomazole. The in vivo inotropic p