1023743-68-1

Basic information

• Product Name: 7-methyl-2-p-tolylquinoxaline
• Synonyms: 7-methyl-2-p-tolylquinoxaline
• CAS NO: 1023743-68-1
• Molecular Weight: 234.301
• Mol File: 1023743-68-1.mol

Chemical Properties

• CAS DataBase Reference: 7-methyl-2-p-tolylquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-methyl-2-p-tolylquinoxaline(1023743-68-1)
• EPA Substance Registry System: 7-methyl-2-p-tolylquinoxaline(1023743-68-1)

Safety Data

• Hazardous Substances Data: 1023743-68-1(Hazardous Substances Data)

Upstream product

• 496-72-0 4-methyl-1,2-diaminobenzene 
• 17263-64-8 2-diazo-1-(4-methylphenyl)ethanone 
• 619-41-0 4-(bromoacetyl)toluene 
• 874-60-2 4-methyl-benzoyl chloride 
• 766-97-2 4-n-methylphenylacetylene 

Relevant articles and documents

Iodine-mediated oxidative annulation for one-pot synthesis of pyrazines and quinoxalines using a multipathway coupled domino strategy

An efficient iodine-mediated oxidative annulation of aryl acetylenes-arylethenes-aromatic ketones with 1,2-diamines for the synthesis of pyrazines and regioselective synthesis of quinoxalines is presented. A multipathway coupled domino approach has been developed for the one-pot synthesis of 1,4-diazines with high functional group compatibility.

A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclisation of 1,2-diamines and phenacyl bromides

A simple, efficient and eco-friendly method has been developed for quinoxaline synthesis from inexpensive and readily available diamines and phenacyl bromides by catalyst- and additive-free protocol.

Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor

A flow method for the synthesis of aliphatic and aromatic diazoketones from acyl chloride precursors has been developed and used to prepare quinoxalines in a multistep sequence without isolation of the potentially explosive diazoketone. The protocol showcases an efficient in-line purification using supported scavengers with time-saving and safety benefits and in particular a reduction in the operator's exposure to carcinogenic phenylenediamines.

A mild and convenient synthesis of quinoxalines via cyclization-oxidation process using DABCO as catalyst

An efficient and general method has been described for the synthesis of quinoxalines by the reaction of 1,2-diamines with phenacyl bromides in the presence of DABCO. The method is suitable for the preparation of functionalized quinoxalines.

First example of Cu(OTf)2-catalyzed synthesis of quinoxalines from α-diazoketones and aryl 1,2-diamines

α-Diazoketones undergo smooth coupling with aryl 1,2-diamines in the presence of 10 mol % of copper(II) triflate to provide the corresponding 2-alkyl- or 2-aryl-quinoxalines in excellent yields with high selectivity. Rh2(OAc)4 is als