1023754-96-2Relevant academic research and scientific papers
The development of a general strategy for the synthesis of tyramine-based natural products by using continuous flow techniques
Achanta, Srinivas,Liautard, Virginie,Paugh, Robert,Organ, Michael G.
supporting information; experimental part, p. 12797 - 12800 (2011/02/22)
A flowing future! A multistep, general flow chemistry protocol has been developed for the preparation of tyramine-based natural products. The process integrates room-temperature reactions with high-temperature Heck coupling reactions, where the heat has been supplied by microwave irradiation. As a proof of concept for 'scaling out' to attain larger quantities of the desired products, the four primary tyramine-based natural products were prepared on a gram scale using this synthetic protocol.
