1024016-74-7Relevant academic research and scientific papers
A benzothiazole-based near-infrared fluorescent probe for sensing SO2 derivatives and viscosity in HeLa cells
Li, Yibing,Zhu, Yilin,Cai, Xuzi,Guo, Jimin,Yao, Cuiping,Pan, Qiling,Wang, Xuefeng,Wang, Kang-Nan
, (2021/01/25)
The unbalanced metabolism of sulfur dioxide can cause various diseases, such as neurological disorders and lung cancer. Until now, some researches revealed that the normal function of lysosomes would be disrupted by its abnormal viscosity. As a signal molecule, sulfur dioxide (SO2) plays an important role in lysosome metabolism. However, the connection of metabolism between the SO2 and viscosity in lysosomes is still unknown. Herein, we developed a benzothiazole-based near-infrared (NIR) fluorescent probe (Triph-SZ), which can monitor the SO2 derivatives and respond to the change of viscosity in lysosomes through two-photon imaging. Triph-SZ present high sensitivity and selectivity fluorescence response with the addition of SO2 derivatives based on the nucleophilic addition, and it also exhibits a sensitive fluorescence enhancement to environmental viscosity, which allows Triph-SZ to be employed to monitor the level of HSO3? and viscosity changes in lysosomes by the two-photon fluorescence lifetime imaging microscopy.
Highly reactive (<1 min) ratiometric probe for selective 'naked-eye' detection of cyanide in aqueous media
Goswami, Shyamaprosad,Manna, Abhishek,Paul, Sima,Aich, Krishnendu,Das, Avijit Kumar,Chakraborty, Shampa
, p. 1785 - 1789 (2013/05/09)
We have designed and synthesized a triphenyl aminebenzothiazole coupled receptor (TBH) that exhibits a selective, sensitive, colorimetric, and ratiometric rapid response toward cyanide anion in aqueous media. The sensing event is explained by spectroscopy along with DFT calculation and CV diagram. Sensor displays a very fast response (- and AcO- in aqueous media.
Synthesis and study of novel benzothiazole derivatives with potential nonlinear optical properties
Sigmundova, Ivica,Zahradnik, Pavol,Loos, Dusan
, p. 1069 - 1093 (2008/12/22)
The synthesis of new benzothiazole push-pull systems as candidates for NLO-phores is described. Spectral (UV/VIS and solvatochromic) and theoretical studies (electronic properties based on semiempirical AM1 and PM3 methods) of the prepared compounds were carried out. The structure and physico-chemical parameters affecting the push-pull character and intramolecular charge transfer (ICT) of the studied compounds have been investigated and compounds with enhanced hyperpolarizability β have been predicted. The benzothiazolium salts were found to be much more effective NLO-phores in comparison with the corresponding neutral benzothiazoles. The 4-NPh2 group is the most effective donor. The extension of conjugated bridge improves the studied NLO characteristics. An additional acceptor group bonded to the heterocycle causes a red shift of λmax but does not increase hyperpolarizability.
