1024586-08-0Relevant academic research and scientific papers
Group exchange between ketones and carboxylic acids through directing group assisted Rh-catalyzed reorganization of carbon skeletons
Lei, Zhi-Quan,Pan, Fei,Li, Hu,Li, Yang,Zhang, Xi-Sha,Chen, Kang,Wang, Xin,Li, Yu-Xue,Sun, Jian,Shi, Zhang-Jie
supporting information, p. 5012 - 5020 (2015/05/05)
The Rh(I)-catalyzed direct reorganization of organic frameworks and group exchanges between carboxylic acids and aryl ketones was developed with the assistance of directing group. Biaryls, alkenylarenes, and alkylarenes were produced in high efficiency from aryl ketones and the corresponding carboxylic acids by releasing the other molecule of carboxylic acids and carbon monoxide. A wide range of functional groups were well compatible. The exchanges between two partners were proposed to take place on the Rh-(III) center of key intermediates, supported by experimental mechanistic studies and computational calculations. The transformation unveiled the new catalytic pathway of the group transfer of two organic molecules.
Iron-catalyzed direct arylation through directed C-H bond activation
Norinder, Jakob,Matsumoto, Arimasa,Yoshikai, Naohiko,Nakamura, Eiichi
, p. 5858 - 5859 (2008/09/19)
An iron-catalyzed C-C bond formation reaction of a nitrogen-containing aromatic compound with an arylzinc reagent takes place at 0 °C in a good to quantitative yield. The reaction involves a C-H bond activation directed by a neighboring nitrogen atom. The important additives in this reaction are 1,10-phenanthroline, tetramethylethylenediamine, and 1,2-dichloro-2-methylpropane, in the absence of which a very low product yield was observed. Copyright
