1024590-59-7

Upstream product

• 864365-18-4 (4R)-2-(3-(trifluoromethyl)benzyl)-4,5-dihydrothiazole-4-carboxylic acid methyl ester 
• 66696-81-9 5-(1-hydroxyoctylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Downstream Products

• 1024590-40-6 (3R)-7-heptyl-5-oxo-8-(3-trifluoromethyl-phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]-pyridine-3-carboxylic acid 
• 1024590-61-1 (3R)-7-heptyl-5-oxo-8-(3-trifluoromethyl-phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]-pyridine-3-carboxylic acid amide 
• 1024590-63-3 (3R)-7-heptyl-5-oxo-8-(3-trifluoromethyl-phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]-pyridine-3-carboxylic acid methylamide 
• 1024590-66-6 (3R)-7-heptyl-6-nitro-5-oxo-8-(3-trifluoromethyl-phenyl)-2,3-dihydro-5H-thiazolo[3,2-a]-pyridine-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

NEW PEPTIDOMIMETIC COMPOUNDS

The present invention relates to new compounds of the formula (I), (II), or (III)wherein R1, R2, R3, R4, R5 and W are as defined herein, and pharmaceutical compositions containing them, and their use

1H-PYRIDINE- 2 -ONE DERIVATIVES USEFUL IN TREATMENT OF PAI-1 RELATED DISORDERS

The claimed invention provides 1H-pyridine-2-one derivatives, inhibitors of PAI-1, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I, II and III may be used in the treatment o