1024598-18-2Relevant academic research and scientific papers
Synthesis of Allylsilanes via Nickel-Catalyzed Cross-Coupling of Silicon Nucleophiles with Allyl Alcohols
Yang, Bo,Wang, Zhong-Xia
supporting information, p. 7965 - 7969 (2019/10/19)
NiCl2(PMe3)2-catalyzed reaction of allyl alcohols with silylzinc reagents, including PhMe2SiZnCl, Ph2MeSiZnCl, and Ph3SiZnCl, was performed, achieving allylsilanes in high yields. Aryl- and heteroaryl-substituted allyl alcohols, (E)-3-arylprop-2-en-1-ols, 1-aryl-prop-2-en-1-ols, and (E)-1-phenylpent-1-en-3-ol can be employed in the transformation. A range of functional groups as well as heteroaryl groups were tolerated. Reaction exhibited high regioselectivity and E/Z-selectivity when 1- or 3-aryl-substituted allyl alcohols were used as the substrates. Reaction of chiral allyl alcohol, (S,E)-1-phenylpent-1-en-3-ol, yielded a configuration-inversion product (R,E)-dimethyl(phenyl)(1-phenylpent-1-en-3-yl)silane.
Intramolecular Friedel-Crafts type reaction of vinyloxiranes linked to an ester group
Nagumo, Shinji,Miura, Toshie,Mizukami, Megumi,Miyoshi, Irie,Imai, Masanori,Kawahara, Norio,Akita, Hiroyuki
experimental part, p. 9884 - 9896 (2010/01/16)
The 7-endo Friedel-Crafts cyclization of arylpropyl vinyloxiranes was found to proceed regio- and stereoselectively to afford polyfunctional seven-membered carbocycles in excellent yields.
Hg(OTf)2-catalyzed arylene cyclization
Namba, Kosuke,Yamamoto, Hirofumi,Sasaki, Ikuo,Mori, Kumiko,Imagawa, Hiroshi,Nishizawa, Muaio
supporting information; experimental part, p. 1767 - 1770 (2009/04/12)
Novel Hg(OTf)2-catalyzed arylene cyclization was achieved with highly efficient catalytic turnover (up to 200 times). The reaction takes place via protonation of allylic hydroxyl group by in situ formed TfOH of an organomercurlc intermediate to
