1024606-12-9Relevant academic research and scientific papers
Enamide synthesis by copper-catalyzed cross-coupling of amides and potassium alkenyltrifluoroborate salts
Bolshan, Yuri,Batey, Robert A.
, p. 2109 - 2112 (2008)
(Chemical Equation Presented) A new partner: Potassium alkenyltrifluoroborate salts undergo coupling with amides to give enamides in the presence of a Cu(OAc)2 catalyst and under mild oxidative conditions (see scheme). The air- and water-stable alkenyltrifluoroborate salts offer a convenient alternative to alkenyl halides as cross-coupling partners. A range of amides undergo coupling including cyclic amides, imides, and carbamates as well as benzamides.
