10249-13-5 Usage
General Description
2-phenethylisoquinolinium bromide is a chemical compound that belongs to the isoquinolinium class of compounds. It is a quaternary ammonium compound that contains a bromide ion. 2-phenethylisoquinolinium bromide has been studied and used in pharmaceutical research due to its potential pharmacological properties, particularly in the field of neuroscience. 2-phenethylisoquinolinium bromide has been investigated for its potential as a neuromuscular blocking agent, and it has also been studied for its potential as an analgesic and anticonvulsant. Its chemical structure and properties make it a potentially valuable compound in the development of new drugs for the treatment of various neurological and neuromuscular disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 10249-13-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,4 and 9 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10249-13:
(7*1)+(6*0)+(5*2)+(4*4)+(3*9)+(2*1)+(1*3)=65
65 % 10 = 5
So 10249-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N/c1-2-6-15(7-3-1)10-12-18-13-11-16-8-4-5-9-17(16)14-18/h1-9,11,13-14H,10,12H2/q+1
10249-13-5Relevant articles and documents
Carbene-catalyzed aerobic oxidation of isoquinolinium salts: Efficient synthesis of isoquinolinones
Wang, Guanjie,Hu, Wanyao,Hu, Zhouli,Zhang, Yuxia,Yao, Wei,Li, Lin,Fu, Zhenqian,Huang, Wei
supporting information, p. 3302 - 3307 (2018/07/29)
A mild and environmentally friendly carbene-catalyzed aerobic oxidation of isoquinolinium salts was successfully realized. Accordingly, a diverse set of isoquinolinones and phenanthridinones was efficiently prepared in good to excellent yields. The mechanistic study indicates that the formation of an aza-Breslow intermediate is the crucial step in this transformation. This reaction features ambient air as the sole oxidant and oxygen source, a broad substrate scope, and excellent functional-group tolerance and proceeds under mild reaction conditions. Furthermore, a highly efficient synthesis of bioactive molecules and natural products including N-methylcrinasiadine, N-isopentylcrinasiadine, N-phenethylcrinasiadine, isoindolo[2,1-b]isoquinolin-5(7H)-one, PJ-34, rac-Gusanlung D, rosettacin, 8-oxopseudopalmatine and ilicifoline B was accomplished.
