1025029-60-0

Basic information

• Product Name: BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER
• Synonyms: BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER;tert-butyl 3-(3-ethoxy-3-oxopropanoyl)azetidine-1-carboxylate;Ethyl b-oxo-1-Boc-3-azetidinepropanoate;1-Boc-3-(3-ethoxy-3-oxopropanoyl)azetidine;3-Azetidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-oxo-, ethyl ester
• CAS NO: 1025029-60-0
• Molecular Formula: C₁₃H₂₁NO₅
• Molecular Weight: 271.32
• Mol File: 1025029-60-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 353.2±32.0 °C(Predicted)
• Appearance: /
• Density: 1.162±0.06 g/cm3(Predicted)
• PKA: 10.28±0.20(Predicted)
• CAS DataBase Reference: BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER(1025029-60-0)
• EPA Substance Registry System: BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER(1025029-60-0)

Safety Data

• Hazardous Substances Data: 1025029-60-0(Hazardous Substances Data)

Usage

General Description

BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER is a chemical compound with the molecular formula C12H19NO5. It is an ethyl ester of 3-azetidinepropanoic acid, which is a derivative of proline. BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various compounds. It is often used as a starting material in the production of pharmaceutical drugs and agrochemicals. BETA-OXO-1-BOC-3-AZETIDINEPROPANOIC ACID ETHYL ESTER has potential applications in the fields of medicine, agriculture, and materials science.

Upstream product

• 6148-64-7 ethyl potassium malonate 
• 142253-55-2 1-(t-butyloxycarbonyl)-azetidine-3-carboxylic acid 
• 2033-24-1 cycl-isopropylidene malonate 
• 64-17-5 ethanol 

Downstream Products

• 1025029-62-2 tert-butyl 3-(2-(2-chlorophenyl)-6-hydroxy-pyrimidin-4-yl)-azetidine-1-carboxylate 

Relevant articles and documents

NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF

It is intended to provide a novel compound having high antitumor activity and low toxicity to normal cells. The present invention provides a pyridone carboxylic acid derivative represented by the following formula (1) or a salt thereof wherein R1 represents a hydrogen atom, a halogen atom or the like; R2 represents a hydrogen atom, a halogen atom or the like; R3 to R6 each represent a hydrogen atom or the like; R7 represents a hydrogen atom or the like; R8 represents a hydrogen atom, a halogen atom, the following formula (a) (wherein Ra1 and Ra2 each represent a hydrogen atom, a hydroxy group, an optionally substituted lower alkyl group or the like) or the like, or R7 and R8 together represent —N—OR10 (wherein R10 represents a hydrogen atom, an optionally substituted lower alkyl group, or an aralkyl group), or R7 and R8 form an optionally substituted 4- to 6-membered saturated hetero ring together with the adjacent carbon atom, or the like; R9 represents a hydrogen atom or the like; X represents a nitrogen atom or the like; and Y represents a nitrogen atom or the like.

AMINOPYRIDINES AND AMINOPYRIMIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES

The present invention relates to substituted pyridine or pyrimidine derivatives useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in