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102503-23-1

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102503-23-1 Usage

General Description

N-(2,4-dimethoxybenzyl)-N-methylamine is a chemical compound with the molecular formula C10H15NO2. It is an organic amine compound, which means it contains nitrogen and is derived from ammonia. This chemical is used in the pharmaceutical industry, specifically as an intermediate in the synthesis of organic compounds and pharmaceutical drugs. It can also be used as a reagent in chemical processes such as the formation of amide bonds and the creation of heterocycles. N-(2,4-dimethoxybenzyl)-N-methylamine is a versatile compound with various applications in the field of organic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 102503-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,5,0 and 3 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 102503-23:
(8*1)+(7*0)+(6*2)+(5*5)+(4*0)+(3*3)+(2*2)+(1*3)=61
61 % 10 = 1
So 102503-23-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO2/c1-11-7-8-4-5-9(12-2)6-10(8)13-3/h4-6,11H,7H2,1-3H3

102503-23-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,4-Dimethoxyphenyl)-N-methylmethanamine

1.2 Other means of identification

Product number -
Other names 1-(2,4-dimethoxyphenyl)-N-methylmethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102503-23-1 SDS

102503-23-1Relevant articles and documents

Synthetic studies to help elucidate the metabolism of the preclinical candidate TBAJ-876—a less toxic and more potent analogue of bedaquiline

Choi, Peter J.,Conole, Daniel,Sutherland, Hamish S.,Blaser, Adrian,Tong, Amy S.T.,Cooper, Christopher B.,Upton, Anna M.,Palmer, Brian D.,Denny, William A.

, (2020)

Bedaquiline is a novel drug approved in 2012 by the FDA for treatment of drug-resistant tuberculosis (TB). Although it shows high efficacy towards drug-resistant forms of TB, its use has been limited by the potential for significant side effects. In particular, bedaquiline is a very lipophilic compound with an associated long terminal half-life and shows potent inhibition of the cardiac potassium hERG channel, resulting in QTc interval prolongation in humans that may result in cardiac arrhythmia. To address these issues, we carried out a drug discovery programme to develop an improved second generation analogue of bedaquiline. From this medicinal chemistry program, a candidate (TBAJ-876) has been selected to undergo further preclinical evaluation. During this evaluation, three major metabolites arising from TBAJ-876 were observed in several preclinical animal models. We report here our synthetic efforts to unequivocally structurally characterize these three metabolites through their independent directed synthesis.

METALLOENZYME INHIBITOR COMPOUNDS

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Page/Page column 301, (2018/09/28)

Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.

Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A2A receptor antagonists

Cole, Andrew G.,Stauffer, Tara M.,Rokosz, Laura L.,Metzger, Axel,Dillard, Lawrence W.,Zeng, Wenguang,Henderson, Ian

scheme or table, p. 378 - 381 (2011/03/18)

The discovery and synthesis of a series of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A2A receptor antagonists from a small-molecule combinatorial library using a high-throughput radioligand-binding assay is described. Antagonists were

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