1025064-41-8 Usage
Uses
(αR)-N-[3-[3-(Difluoromethyl)phenyl]propyl]-α-methyl-1-naphthalenemethanamine is an impurity of Cinacalcet (C441800); an oral calcimimetic agent that modulates the calcium-sensing receptor, reduces parathyroid hormone (PHT) secretion, and lowers serum calcium and phosphorus concentrations in patients with endstage renal disease (ESRD) and secondary hyperparathyroidism (HPT).
Check Digit Verification of cas no
The CAS Registry Mumber 1025064-41-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,5,0,6 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1025064-41:
(9*1)+(8*0)+(7*2)+(6*5)+(5*0)+(4*6)+(3*4)+(2*4)+(1*1)=98
98 % 10 = 8
So 1025064-41-8 is a valid CAS Registry Number.
1025064-41-8Relevant articles and documents
PROCESSES FOR THE PREPARATION OF CINACALCET
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Page/Page column 42, (2008/12/05)
There are described several processes for making a free base of cinacalcet. One of the described processes goes through an intermediate of the formula (II) where R1 and R2 are both hydrogen, or R1 and R2, together, form a double bond.
