10252-66-1 Usage
General Description
4-[(Isopropylamino)sulfonyl]benzoic acid is a chemical compound with the formula C12H17NO4S. It is a white to off-white crystalline powder and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound is also known for its anti-inflammatory and analgesic properties, and it is often used in pain relief medications. Its structure consists of a benzoic acid core with a sulfonyl group attached to an isopropylamino group. 4-[(Isopropylamino)sulfonyl]benzoic acid is compatible with other organic and inorganic chemicals and solvents, making it a versatile compound in the field of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 10252-66-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,5 and 2 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10252-66:
(7*1)+(6*0)+(5*2)+(4*5)+(3*2)+(2*6)+(1*6)=61
61 % 10 = 1
So 10252-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO4S/c1-7(2)11-16(14,15)9-5-3-8(4-6-9)10(12)13/h3-7,11H,1-2H3,(H,12,13)/p-1
10252-66-1Relevant articles and documents
Functionalization of α-C(sp3)?H Bonds in Amides Using Radical Translocating Arylating Groups
Radhoff, Niklas,Studer, Armido
supporting information, p. 3561 - 3565 (2021/01/04)
α-C?H arylation of N-alkylamides using 2-iodoarylsulfonyl radical translocating arylating (RTA) groups is reported. The method allows the construction of α-quaternary carbon centers in amides. Various mono- and disubstituted RTA-groups are applied to the arylation of primary, secondary, and tertiary α-C(sp3)?H-bonds. These radical transformations proceed in good to excellent yields and the cascades comprise a 1,6-hydrogen atom transfer, followed by a 1,4-aryl migration with subsequent SO2 extrusion.