1025324-88-2Relevant academic research and scientific papers
Carbamoyl translocations by an anionic ortho-fries and cumulenolate α-acylation pathway: Regioselective synthesis of polysubstituted chromone 3- and 8-carboxamides
Macklin, Todd K.,Panteleev, Jane,Snieckus, Victor
supporting information; experimental part, p. 2097 - 2101 (2009/02/06)
(Chemical Equation Presented) Completing the circle: A synthesis of chromone 3- and 8-carboxamides (3 and 4) from 2-but-2-ynoyl aryl O-carbamates 1 has been achieved via common intermediate 2 in a regioselective manner. Repetitive metalation reactions and an iridium-catalyzed B22pin 2 borylation lead to the construction of polysubstituted chromones, which are key components of many bioactive compounds.
