1025358-49-9Relevant articles and documents
Preliminary SAR analysis of novel antiproliferative N6,5′-bis-ureidoadenosine derivatives
Peterson, Matt A.,Oliveira, Marcelio,Christiansen, Michael A.,Cutler, Christopher E.
scheme or table, p. 6775 - 6779 (2010/06/17)
A preliminary library of novel N6,5′-bis-ureidoadenosine analogs and related derivatives was prepared and tested for activity against the NCI 60 panel of human cancers. A 2′-O-TBS group was found to be necessary, but not sufficient, for optimal
Design, synthesis, and antiviral evaluation of some 3′-carboxymethyl- 3′-deoxyadenosine derivatives
Peterson, Matt A.,Ke, Pucheng,Shi, Houguang,Jones, Carl,McDougall, Brenda R.,Robinson Jr., W. Edward
, p. 499 - 519 (2008/02/13)
3′-Carboxymethyl-3′-deoxyadenosine derivatives were prepared from 2′-O-TBDMS-3′-[(ethoxycarbonyl)methyl]-3′-deoxyadenosine (1) via simple and efficient procedures. Conversion of 1 to its 5′-azido-5′-deoxy derivative 5 was accomplished via a novel one-pot