1025451-30-2Relevant academic research and scientific papers
α/γ4-Hybrid peptide helices: Synthesis, crystal conformations and analogy with the α-helix
Bandyopadhyay, Anupam,Jadhav, Sandip V.,Gopi, Hosahudya N.
, p. 7170 - 7172 (2012/08/08)
Synthesis, crystal conformations of α/γ4-hybrid peptide helices containing proteinogenic amino acid side-chains, and the analogy with the α-helix are reported. Results suggest that α/ γ4-hybrid peptides adopted helical conformations
Novel CADD-based peptidyl vinyl ester derivatives as potential proteasome inhibitors
Mou, Ke,Xu, Bo,Ma, Chao,Yang, Xiaoming,Zou, Xiaomin,Lue, Yang,Xu, Ping
, p. 2198 - 2202 (2008/12/22)
A series of peptidyl vinyl ester derivatives bearing three different P1 substitutions as potential proteasome inhibitors were studied. The target molecules were designed based on CADD (computer aided drug design) protocol and synthesized. Their activities
