1025454-76-5

Basic information

• Product Name: (E)-1-(1H-benzoimidazol-5-yl)-5-(4-chloro-phenyl)-4-cyclopentylimino-imidazolidin-2-one
• Synonyms: (E)-1-(1H-benzoimidazol-5-yl)-5-(4-chloro-phenyl)-4-cyclopentylimino-imidazolidin-2-one
• CAS NO: 1025454-76-5
• Molecular Weight: 393.876
• Mol File: 1025454-76-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(1H-benzoimidazol-5-yl)-5-(4-chloro-phenyl)-4-cyclopentylimino-imidazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(1H-benzoimidazol-5-yl)-5-(4-chloro-phenyl)-4-cyclopentylimino-imidazolidin-2-one(1025454-76-5)
• EPA Substance Registry System: (E)-1-(1H-benzoimidazol-5-yl)-5-(4-chloro-phenyl)-4-cyclopentylimino-imidazolidin-2-one(1025454-76-5)

Safety Data

• Hazardous Substances Data: 1025454-76-5(Hazardous Substances Data)

Upstream product

• 590-28-3 potassium cyanate 
• 934-22-5 5-aminobenzimidazole 
• 104-88-1 4-chlorobenzaldehyde 
• 68498-54-4 isocyanocyclopentane 

Relevant articles and documents

NOVEL INHIBITORS OF GLUTAMINYL CYCLASE

The present invention relates to compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein R1 represents heteroaryl; -carbocyclyl-heteroaryl; -alkenylheteroaryl or -alkylheteroaryl; R2 represents alkyl, which may optionally be substituted by hydroxy; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl and hydroxy; aryl; -aryl-heteroaryl; -heteroaryl-aryl; -aryl-heterocyclyl; H; heteroaryl; or heterocyclyl, which may optionally be substituted by one or more groups selected from alkyl, oxo and hydroxy; R3represents alkyl, which may optionally be substituted by one of more groups selected from alkoxy, amine, hydroxy and -C(O)Oalkyl; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl, haloalkyl, alkoxy, amine, hydroxy and -C(O)Oalkyl; -alkyl-aryl; -alkyl(aryl)2; -alkyl-heteroaryl; -alkyl(heteroaryl)2; -alkyl(heteroaryl)(aryl); -aryl-O-aryl; aryl; heterocyclyl, -alkyl-C(O)-heterocyclyl, -alkyl-heterocyclyl, -alkyl-C(O)-NR5-heterocyclyl or -alkyl(heterocyclyl)2 in any of which groups heterocyclyl may be optionally substituted by one or more groups selected from alkyl, hydroxy and oxo; -heteroaryl; or -hydroxyalkylaryl; R4 represents H or C1-3 alkyl; R5 represents H or C1-3 alkyl; and X represents O or S.