102548-95-8

Upstream product

• 58995-82-7 2-(4-benzyloxyphenyl)-1H-indole 
• 69116-35-4 4'-hydroxyacetophenone phenylhydrazone 
• 603-76-9 1-methylindole 
• 19578-68-8 4-(4-benzyloxyphenyl) iodide 
• 40643-14-9 2-(4'-hydroxy-phenyl)-indole 

Relevant academic research and scientific papers

Room temperature and phosphine free palladium catalyzed direct C-2 arylation of indoles

We report the first room-temperature direct C-2 arylation of indoles with iodoarenes by using a highly electrophilic palladium catalyst generated in situ from Pd(OAc)2 and a silver carboxylate. These mild conditions permit a broad set of functionalities both in the indole and in the aryl iodide units such as free alcohols, phenols, aldehydes, bromides, or nitriles, thus allowing the synthesis of a variety of novel compounds in excellent yields. Copyright