1025504-76-0 Usage
Uses
Used in Pharmaceutical Industry:
(S)-2-benzyloxycarbonyl-amino-3-methylbutyric acid-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1,a]isoquinolin-2-yl ester is used as an intermediate in the synthesis of Valbenzine (V087000), a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor. (S)-2-benzyloxycarbonyl-amino-3-methylbutyric acid-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester is utilized in the treatment of tardive dyskinesia, a movement disorder characterized by involuntary muscle movements.
Used in Chemical Synthesis:
Due to its complex structure and various functional groups, (S)-2-benzyloxycarbonyl-amino-3-methylbutyric acid-(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester can be employed as a building block or a key intermediate in the synthesis of other complex organic molecules, particularly in the fields of pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
The compound's unique structure and properties make it a valuable tool for researchers in the fields of organic chemistry, medicinal chemistry, and chemical biology. It can be used to study various aspects of molecular recognition, receptor binding, and enzyme inhibition, among other applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1025504-76-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,5,5,0 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1025504-76:
(9*1)+(8*0)+(7*2)+(6*5)+(5*5)+(4*0)+(3*4)+(2*7)+(1*6)=110
110 % 10 = 0
So 1025504-76-0 is a valid CAS Registry Number.
1025504-76-0Relevant academic research and scientific papers
CRYSTALLINE VALBENAZINE FREE BASE
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, (2018/08/03)
The present disclosure generally relates to crystalline valbenazine. The present disclosure also generally relates to a pharmaceutical composition comprising crystalline valbenazine, as well of methods of using crystalline valbenazine in the treatment of
SUBSTITUTED 3-ISOBUTYL-9, 10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-A] ISOQUINOLIN-2-OL COMPOUNDS AND METHODS RELATING THERETO
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Page/Page column 14-15, (2008/12/05)
Substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol compounds are disclosed that are inhibitors of the vesicular monoamine transporter 2 (VMAT2). The compounds of this invention have the structure (I): wherein R1 is as defined herein, including stereoisomers and pharmaceutically acceptable salts and solvates thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use in a subject in need thereof.
