1025556-01-7Relevant articles and documents
The role of lipophilicity in determining binding affinity and functional activity for 5-HT2A receptor ligands
Parker, Matthew A.,Kurrasch, Deborah M.,Nichols, David E.
, p. 4661 - 4669 (2008)
The lipophilicity of a set of 5-HT2A ligands was determined using immobilized-artificial-membrane chromatography, a method that generates values well correlated with octanol-water partition coefficients. For agonists, a highly significant linea