1025760-25-1Relevant articles and documents
Palladium-catalyzed oxidative cyclization of tertiary enamines for synthesis of 1,3,4-trisubstituted pyrroles and 1,3-disubstituted indoles
Lian, Xiao-Li,Ren, Zhi-Hui,Wang, Yao-Yu,Guan, Zheng-Hui
supporting information, p. 3360 - 3363 (2014/07/08)
A novel and efficient palladium-catalyzed intramolecular oxidative cyclization of tertiary enamines for the synthesis of 1,3,4-trisubstituted pyrroles and 1,3-disubstituted indoles has been developed. Trifluoroacetic acid plays an important role in the reaction. A series of pyrroles and indoles with substitution patterns that are not easily accessible by traditional routes were synthesized in good yields under mild conditions.
Regioselective Rh-catalyzed direct carbonylation of indoles to synthesize indole-3-carboxylates
Lang, Rui,Wu, Junliang,Shi, Lijun,Xia, Chungu,Li, Fuwei
supporting information; experimental part, p. 12553 - 12555 (2012/02/02)
Rh-catalyzed C-H carbonylation of indoles under 1 atm of CO has been achieved. Various substituted indoles and indole with free N-H could be carboxylated with linear- and/or cyclic-alcohol to give the desired indole-3-carboxylates with up to 92% yield. A mechanism involving Rh III initiated C-H metallation is proposed.
Copper-catalyzed synthesis of esters from ketones. Alkyl group as a leaving group
Nakatani, Yuji,Koizumi, Yuichiro,Yamasaki, Ryu,Saito, Shinichi
supporting information; experimental part, p. 2067 - 2070 (2009/04/08)
The conversion of ketones to esters has been achieved through the use of Cu catalyst and tetrabutylammonium nitrite. This reaction involves the activation of the less activated C-C bond, and the alkyl group is removed as a leaving group. Various isopropyl ketones are found to be good substrates for this reaction.