1025765-55-2Relevant academic research and scientific papers
Synthesis of conformationally constrained elimino acid derivatives via ring-closing metathesis
Kotha, Sambasivarao,Khedkar, Priti
, p. 975 - 979 (2008/09/18)
Conformationally constrained amino acid derivatives are useful in the synthesis of peptidomimetics. Seven-, and eightmembered conformationally constrained α-imino acid derivatives have been prepared via RCM (ring-closing metathesis). Interestingly, attempts to achieve the synthesis of nine-membered imino acid derivative resulted in the formation of dimeric, 18membered macrocyclic bis-a-imino acid derivative.
