1025814-91-8

Upstream product

• 143745-20-4 methyl 5-fluoro-2-pivaloyl-5,8-dideazaisopteroate 
• 143745-21-5 methyl 5-fluoro-5,8-dideazaisopteroate 
• 143745-19-1 6-amino-3,4-dihydro-5-fluoro-4-oxo-2-(pivaloylamino)quinazoline 
• 142465-05-2 2-amino-3,4-dihydro-5-fluoro-4-oxoquinazoline 
• 119584-70-2 2,4-diamino-5-fluoroquinazoline 
• 143745-22-6 5-fluoro-5,8-dideazaisopteroic acid 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 143745-23-7 N^δ-(tert-butyloxycarbonyl)-N^α-(5-fluoro-5,8-dideazaisopteroyl)-L-ornithine 
• 143745-10-2 N^α-(5-fluoro-5,8-dideazaisopteroyl)-L-ornithine 

Relevant academic research and scientific papers

Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogues of folic acid bearing a terminal L-ornithine residue

Five new N(α)-(5,8-dideazapteroyl)-L-ornithines have been prepared using multistep synthetic sequences. These include N(α)-[5-(trifluoromethyl)-5,8- dideazapteroyl]-L-ornithine, 3, as well as N(α)-[5-(trifluoromethyl)-5,8- dideazaisopteroyl]-L-ornithine,