1025824-91-2Relevant academic research and scientific papers
Synthesis anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1- jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 3
Breslin,Kukla,Ludovici,Mohrbacher,Ho,Miranda,Rodgers,Hitchens,Leo,Gauthier,Ho,Scott,De Clercq,Pauwels,Andries,Janssen,Janssen
, p. 771 - 793 (2007/10/02)
4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO), 1, have been shown to significantly inhibit HIV-1 replication in vitro by interfering with the virus's reverse transcriptase enzyme. They have also demonstrated potential cl
