1025867-86-0Relevant academic research and scientific papers
Synthesis of dihydrothieno[2,3-b]pyridines based on titanium(IV) chloride-mediated Michael reactions of 2-amino-4,5-dihydro-3- thiophenecarbonitriles with α,β-unsaturated ketones
Maruoka, Hiroshi,Yamazaki, Motoyoshi,Tomioka, Yukihiko
, p. 641 - 646 (2007/10/03)
2-Amino-4,5-dihydro-3-thiophenecarbonitriles 1a-c reacted with α,β-unsaturated ketones (e.g. methyl vinyl ketone 2 and benzalacetone 3) in the presence of titanium(IV) chloride to give the corresponding Michael adducts 4a-c and 5a-c. Thermal treatment of
