1025875-27-7Relevant academic research and scientific papers
INDAZOLYL ESTER AND AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS
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Example 90, (2008/12/06)
Compounds of formula (I): The present invention relates to novel indazolyl ester or amide derivatives, to pharmaceutical compositions comprising such derivatives, to processes for preparing such novel derivatives and to the use of such derivatives as medicaments
A highly stereoselective synthesis of optically active trisubstituted 1,2-ethylenediamines: The first example of Grignard addition to N-diphenylphosphinoyl ketimines derived from amino acids
Kohmura, Yoshinori,Mase, Toshiaki
, p. 6329 - 6334 (2007/10/03)
The efficient synthesis of optically active trisubstituted 1,2-ethylenediamines is described. Addition of aryl and/or alkyl Grignard reagents to α-amino N- diphenylphosphinoyl ketimines derived from α-amino acids was demonstrated to afford the desired tri
