10259-30-0

Basic information

• Product Name: Benzoic acid, 2-hydroxy-, 4-broMophenyl ester
• Synonyms: Benzoic acid, 2-hydroxy-, 4-broMophenyl ester
• CAS NO: 10259-30-0
• Molecular Formula: C₁₃H₉BrO₃
• Molecular Weight: 293.11276
• Mol File: 10259-30-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 2-hydroxy-, 4-broMophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-hydroxy-, 4-broMophenyl ester(10259-30-0)
• EPA Substance Registry System: Benzoic acid, 2-hydroxy-, 4-broMophenyl ester(10259-30-0)

Safety Data

• Hazardous Substances Data: 10259-30-0(Hazardous Substances Data)

Upstream product

• 106-41-2 4-bromo-phenol 
• 444-30-4 2-(trifluoromethyl)phenol 
• 330793-13-0 2?(4?bromophenoxy)benzonitrile 
• 394-47-8 2-fluorobenzonitrile 
• 88-67-5 2-Iodobenzoic acid 

Relevant articles and documents

Cerium photocatalyzed radical smiles rearrangement of 2-aryloxybenzoic acids

We report herein a cerium photocatalyzed aryl migration from an aryl ether to a carboxylic acid group through radical-Smiles rearrangement. This operationally simple protocol utilizes inexpensive CeCl3as a photocatalyst and converted a variety of 2-aryloxybenzoic acids into aryl-2-hydroxybenzoates in good yields.

Efficient Aryl Migration from an Aryl Ether to a Carboxylic Acid Group To Form an Ester by Visible-Light Photoredox Catalysis

We have developed a highly efficient aryl migration from an aryl ether to a carboxylic acid group through retro-Smiles rearrangement by visible-light photoredox catalysis at ambient temperature. Transition metals and a stoichiometric oxidant and base are avoided in the transformation. Inspired by the high efficiency of this transformation and the fundamental importance of C?O bond cleavage, we developed a novel approach to the C?O cleavage of a biaryl ether to form two phenolic compounds, as demonstrated by a one-pot, two-step gram-scale reaction under mild conditions. The aryl migration exhibits broad scope and can be applied to the synthesis of pharmaceutical compounds, such as guacetisal. Primary mechanistic studies indicate that the catalytic cycle occurs by a reductive quenching pathway.