102591-74-2Relevant academic research and scientific papers
Oxovanadium(v)-catalyzed oxidative cross-coupling of enolates using O2as a terminal oxidant
Osafune, Yuma,Jin, Yuqing,Hirao, Toshikazu,Tobisu, Mamoru,Amaya, Toru
, p. 11697 - 11700 (2020/10/19)
The oxovanadium(v)-catalyzed oxidative cross-coupling of enolates using O2 as a terminal oxidant is reported, where a boron enolate and a silyl enol ether were employed as enolates. The redox behavior of V(v/iv) in this reaction under O2 was investigated by ESR and 51V NMR experiments.
Selective intermolecular oxidative cross-coupling of enolates
Amaya, Toru,Maegawa, Yusuke,Masuda, Takaya,Osafune, Yuma,Hirao, Toshikazu
, p. 10072 - 10075 (2015/09/01)
Selective intermolecular oxidative cross-coupling of enolates, which is a bond-forming reaction between carbanion equivalents, remains as an unsolved issue despite its potential utility for the direct synthesis of unsymmetrical 1,4-diones. The main difficulty derives from the unavoidable homo-coupling. Our strategy depends on the selective one-electron oxidation of one enolate to afford an electrophilic carbonyl α-radical species, followed by trapping with another enolate. The present study demonstrates the selective oxovanadium(V)-induced cross-coupling between boron and silyl enolates.
