1025941-19-8

Basic information

• Product Name: (E)-3-{3-[2-(4-Fluoro-phenyl)-ethoxy]-6-methyl-1-oxy-pyridin-2-yl}-acrylic acid methyl ester
• CAS NO: 1025941-19-8
• Molecular Weight: 331.344
• Mol File: 1025941-19-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-{3-[2-(4-Fluoro-phenyl)-ethoxy]-6-methyl-1-oxy-pyridin-2-yl}-acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-{3-[2-(4-Fluoro-phenyl)-ethoxy]-6-methyl-1-oxy-pyridin-2-yl}-acrylic acid methyl ester(1025941-19-8)
• EPA Substance Registry System: (E)-3-{3-[2-(4-Fluoro-phenyl)-ethoxy]-6-methyl-1-oxy-pyridin-2-yl}-acrylic acid methyl ester(1025941-19-8)

Safety Data

• Hazardous Substances Data: 1025941-19-8(Hazardous Substances Data)

Upstream product

• 180208-43-9 (E)-3-(3-hydroxy-6-methyl-2-pyridinyl)-2-propenoic acid methyl ester 
• 7589-27-7 2-(4-Fluorophenyl)ethanol 
• 66497-42-5 3-hydroxy-6-methylpicolinaldehyde 
• 1027737-69-4 (E)-3-{3-[2-(4-Fluoro-phenyl)-ethoxy]-6-methyl-pyridin-2-yl}-acrylic acid methyl ester 

Downstream Products

• 1026677-57-5 (E)-methyl 3-[3-[2-(4-fluorophenyl)ethyloxy]-6-[(2,6-dichlorophenylthio)methyl]-2-pyridinyl]-2-propenoate 

Relevant articles and documents

(E)-3-[6-[[(2,6-dichlorophenyl)thio]methyl]-3-(2-phenylethoxy)-2- pyridinyl]-2-propenoic acid: A high-affinity leukotriene B4 receptor antagonist with oral antiinflammatory activity

An extensive structure-activity study based around the high-affinity leukotriene B4 (LTB4) receptor antagonist SB 201146 (1) led to the identification of (E)-3-[6-[[(2,6-dichlorophenyl)thio]methyl]-3-(2- phenylethoxy)-2-pyridinyl]-2-