102595-95-9Relevant articles and documents
Hydrogen bonds induced polymorphism of pyrazoline derivative: Crystal structures, thermal and optical-physical properties
Diao, Guowang,Feng, Qi,Huan, Wenhui,Shen, Chao
, (2020)
In this study, 1-acetyl-3-(3-hydroxyphenyl)-5-(9-anthracenyl)-2-pyrazoline (AHAP) was synthesized and afforded two types of polymorphs. Single crystal X-ray analyses revealed that AHAP molecules connect with each other in a head-to-tail fashion through O-H?O hydrogen bonds between the carbonyl and hydroxyl groups. However, through the above intermolecular interactions and stacking mode, the one-dimensional chain motifs are formed in the α polymorph and cyclic tetramers are formed in the β polymorph, which constitute their crystal structures as units. Compared with solvent-free α polymorph, the unit cell of the β polymorph includes a small region of disordered solvent molecules. CrystalExplorer program, Differential scanning calorimetry (DSC) and thermogravimetric thermal analysis (TGA) experiments revealed that the voids should be inside the tetramers and each void contains one disordered solvent molecule. 1H NMR spectra conformed the type of the disordered solvent molecule is consistent with the crystalline liquid phase. The optical-physical properties of the two polymorphs were also investigated. They emit similar fluorescence, which is assigned to monomer emission of anthracene, due to the monomer arrangement of anthracene fluorophores in the two polymorphs.
Synthesis and pharmacological evaluation of some novel 2-pyrazolines bearing benzenesulfonamide as anti-inflammatory and blood glucose lowering agents
Ovais, Syed,Bashir, Rafia,Yaseen, Shafiya,Rathore, Pooja,Samim, Mohammed,Javed, Kalim
, p. 1378 - 1385 (2013/04/10)
A series of novel pyrazolines (2a-l) bearing benzenesulfonamide moiety were synthesized by condensing appropriate chalcone (1a-l) with 4- hydrazinobenzenesulfonamide hydrochloride. Structure of all novel synthesized compounds was characterized on basis of
