1025958-84-2Relevant academic research and scientific papers
Sulfonate-containing thiiranes as selective gelatinase inhibitors
Testero, Sebastian A.,Lee, Mijoon,Staran, Rachel T.,Espahbodi, Mana,Llarrull, Leticia I.,Toth, Marta,Mobashery, Shahriar,Chang, Mayland
scheme or table, p. 177 - 181 (2011/04/12)
Matrix metalloproteinases (MMPs) are important zinc-dependent endopeptidases. Two members of this family of enzymes called gelatinases (MMP-2 and MMP-9) have been implicated in a number of human diseases, including cancer, neurological and cardiovascular
INHIBITORS OF MATRIX METALLOPROTEINASES
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Page/Page column 105, (2008/06/13)
The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.
