1025963-03-4Relevant articles and documents
Synthesis of E-aryl ethenesulfonamides: A simple one-pot, two-step procedure from 1-hydroxy-1-arylalkanes
Aramini, Andrea,Cesta, Maria C.,Coniglio, Silvia,Bijani, Christian,Colagioia, Sandro,D'Elia, Valerio,Allegretti, Marcello
, p. 7911 - 7914 (2007/10/03)
The unusual reactivity of 1-phenyl-1-ethane-sulfonic acid in thionyl chloride was investigated. Mechanistic considerations led us to set up a new and efficient synthesis of E-arylethenesulfonamides starting from 1-hydroxy-1-arylalkanes. The easy availability of the starting materials and the straightforward, one-pot procedure make this process an attractive method for the preparation of these compounds currently largely employed in chemical and pharmaceutical fields.