1025992-48-6

Basic information

• Product Name: 4-(3,5-Dichlorophenyl)benzonitrile
• Synonyms: 4-(3,5-Dichlorophenyl)benzonitrile
• CAS NO: 1025992-48-6
• Molecular Formula: C₁₃H₇Cl₂N
• Molecular Weight: 248.10738
• Mol File: 1025992-48-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(3,5-Dichlorophenyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,5-Dichlorophenyl)benzonitrile(1025992-48-6)
• EPA Substance Registry System: 4-(3,5-Dichlorophenyl)benzonitrile(1025992-48-6)

Safety Data

• Hazardous Substances Data: 1025992-48-6(Hazardous Substances Data)

Upstream product

• 67492-50-6 (3,5-dichlorophenyl)boronic acid 
• 623-00-7 4-bromobenzenecarbonitrile 

Relevant articles and documents

Palladium-catalyzed decarbonylative Suzuki-Miyaura cross-coupling of amides by carbon-nitrogen bond activation

Palladium-catalyzed Suzuki-Miyaura cross-coupling or aryl halides is widely employed in the synthesis of many important molecules in synthetic chemistry, including pharmaceuticals, polymers and functional materials. Herein, we disclose the first palladium-catalyzed decarbonylative Suzuki-Miyaura cross-coupling of amides for the synthesis of biaryls through the selective activation of the N-C(O) bond of amides. This new method relies on the precise sequence engineering of the catalytic cycle, wherein decarbonylation occurs prior to the transmetallation step. The reaction is compatible with a wide range of boronic acids and amides, providing valuable biaryls in high yields (>60 examples). DFT studies support a mechanism involving oxidative addition, decarbonylation and transmetallation and provide insight into high N-C(O) bond activation selectivity. Most crucially, the reaction establishes the use of palladium catalysis in the biaryl Suzuki-Miyaura cross-coupling of the amide bond and should enable the design of a wide variety of cross-coupling methods in which palladium rivals the traditional biaryl synthesis from aryl halides and pseudohalides.

COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME

The present application relates to a compound, and an organic electronic device including the same. The compound is represented by chemical formula 1. In the chemical formula 1, at least one of X_1 to X_6 is N, and the remainder is the same or different from each other and is independently N or CR. R is hydrogen. R_1 to R_4 are the same or different from each other, and are independently a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted heterocyclic group. At least one of R_6 to R_10 is a cyano group (-CN), and the remainder is hydrogen. L is a directly bond, a substituted or unsubstituted arylene group, or a substituted or unsubstituted divalent heterocyclic group.COPYRIGHT KIPO 2017