1026-60-4Relevant academic research and scientific papers
Synthesis of 5-bromomethylisoxazoles and their reactions with secondary amines
Aliev
, p. 1192 - 1195 (2007/10/03)
Treating R-3-chloro-4-bromo-2-buten-1-ones with hydroxylamine hydrochloride afforded 3-alkyl(aryl, furyl)-5-bromomethylisoxazoles. By reaction of the latter with secondary amines new previously unknown aminoisoxazoles were synthesized. 2005 Pleiades Publi
Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: Synthesis, spectroscopic discrimination, and muscarinic activity
Dannhardt,Lambrecht,Laufer,Mutschler,Schweiger
, p. 437 - 443 (2007/10/02)
The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic
