102601-36-5 Usage
Uses
Used in Biochemistry Research:
Z-ALA-GLU-OH is used as a building block for the synthesis of specific peptide sequences, allowing researchers to study enzyme mechanisms and protein-protein interactions. Its presence as a protected amino acid sequence facilitates controlled synthesis processes in the laboratory.
Used in Pharmaceutical Research and Development:
Z-ALA-GLU-OH serves as a starting material for the production of pharmaceutical drugs, contributing to the development of new therapeutic agents. Its role in drug synthesis is crucial for creating molecules with specific biological activities and potential medicinal applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, Z-ALA-GLU-OH is used with its protecting group to prevent unwanted reactions at specific functional groups. This feature is essential for achieving precise and controlled outcomes in the synthesis of complex organic molecules.
Overall, Z-ALA-GLU-OH is an important chemical component with diverse applications across various industries, including biochemistry, pharmaceuticals, and chemical synthesis, due to its unique structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 102601-36-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,6,0 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 102601-36:
(8*1)+(7*0)+(6*2)+(5*6)+(4*0)+(3*1)+(2*3)+(1*6)=65
65 % 10 = 5
So 102601-36-5 is a valid CAS Registry Number.
102601-36-5Relevant academic research and scientific papers
α-N-Protected dipeptide acids: A simple and efficient synthesis via the easily accessible mixed anhydride method using free amino acids in DMSO and tetrabutylammonium hydroxide
Verardo,Gorassini
, p. 315 - 324 (2013/06/05)
The importance of dipeptides both in medicinal and pharmacological fields is well documented and many efforts have been made to find simple and efficient methods for their synthesis. For this reason, we have investigated the synthesis of α-N-protected dipeptide acids by reacting the easily accessible mixed anhydride of α-N-protected amino acids with free amino acids under different reaction conditions. The combination of TBA-OH and DMSO has been found to be the best to overcome the low solubility of amino acids in organic solvents. Under these experimental conditions, the homogeneous phase condensation reaction occurs rapidly and without detectable epimerization. The present method is also applicable to side-chain unprotected Tyr, Trp, Glu, and Asp but not Lys. This latter residue is able to engage two molecules of mixed anhydride giving the corresponding isotripeptide. Moreover, the applicability of this protocol for the synthesis of tri- and tetrapeptides has been tested. This approach reduces the need for protecting groups, is cost effective, scalable, and yields dipeptide acids that can be used as building blocks in the synthesis of larger peptides.
