1026122-16-6Relevant articles and documents
Convenient Preparations and Michael Reactions of 4-Fluoroalkylated But-2-en-4-olides
Yoshida, Masato,Imai, Rihoko,Komatsu, Yuji,Morinaga, Yoshihiro,Kamigata, Nobumasa,Iyoda, Masahiko
, p. 501 - 504 (1993)
Trifluoromethyl, heptafluoropropyl and chlorodifluoromethyl substituted but-2-en-4-olides have been prepared both from 2-trimethylsiloxyfuran by fluoroalkylation with the corresponding bis(fluoroalkanoyl) peroxide and from 2-fluoroalkylfuran by oxidation with m-nitrobenzenesulfonyl peroxide. 4-Difluoromethylbut-2-en-4-olide was also prepared by chlorodifluoromethylation of 2-methoxyfuran followed by reduction of the chlorine.The 4-trifluoromethylated butenolide thus prepared, could be readily converted into the anion by treatment with weak base.The anion so formed then reacted with electron-deficient olefins to give 4,4-disubstituted butenolides.
