102613-18-3

Basic information

• Product Name: 3-(4-butoxy-3-chlorobenzyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
• CAS NO: 102613-18-3
• Molecular Formula: C₁₅H₁₆ClFN₂O₃
• Molecular Weight: 326.7505
• Mol File: 102613-18-3.mol
• Article Data: 0

Chemical Properties

• Density: 1.34g/cm³
• Refractive Index: 1.579
• CAS DataBase Reference: 3-(4-butoxy-3-chlorobenzyl)-5-fluoropyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-butoxy-3-chlorobenzyl)-5-fluoropyrimidine-2,4(1H,3H)-dione(102613-18-3)
• EPA Substance Registry System: 3-(4-butoxy-3-chlorobenzyl)-5-fluoropyrimidine-2,4(1H,3H)-dione(102613-18-3)

Safety Data

• Hazardous Substances Data: 102613-18-3(Hazardous Substances Data)

Usage

General Description

3-(4-butoxy-3-chlorobenzyl)-5-fluoropyrimidine-2,4(1H,3H)-dione, also known as leflunomide, is a pharmaceutical compound used as an immunosuppressive agent and disease-modifying antirheumatic drug (DMARD) for the treatment of rheumatoid arthritis. It works by inhibiting the synthesis of pyrimidines, which are essential for the proliferation of T cells and B cells in the immune system. Leflunomide is prescribed to reduce inflammation and slow down the progression of joint damage in patients with rheumatoid arthritis. It is typically taken orally and has a long half-life in the body, requiring careful monitoring and management of potential side effects and interactions with other medications. Leflunomide is considered an important treatment option for rheumatoid arthritis and has shown effectiveness in clinical trials and real-world use.