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Nelonicline is a pharmaceutical compound that functions as a selective agonist for the alpha-7 nicotinic acetylcholine receptor, playing a crucial role in neurotransmitter release and cognitive enhancement. It has demonstrated potential in treating cognitive impairments linked to a range of neurological and psychiatric conditions, with a promising safety profile in early clinical trials.

1026134-63-3

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1026134-63-3 Usage

Uses

Used in Pharmaceutical Industry:
Nelonicline is used as a therapeutic agent for cognitive impairments associated with neurological and psychiatric conditions due to its ability to selectively activate the alpha-7 nicotinic acetylcholine receptor, thereby enhancing cognitive function.
Used in Schizophrenia Treatment:
Nelonicline is used as a treatment for cognitive symptoms in schizophrenia, as it has shown potential to improve the condition by modulating neurotransmitter release and cognitive function.
Used in Alzheimer's Disease Management:
Nelonicline is used as a potential treatment for Alzheimer's disease to alleviate cognitive decline, leveraging its action on the alpha-7 nicotinic acetylcholine receptor to support neurotransmission and cognitive health.
Used in Attention-Deficit Hyperactivity Disorder (ADHD) Therapy:
Nelonicline is used as a therapeutic option for ADHD to address cognitive impairments and enhance attention and focus, capitalizing on its role in neurotransmitter regulation and cognitive function enhancement.

Check Digit Verification of cas no

The CAS Registry Mumber 1026134-63-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,6,1,3 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1026134-63:
(9*1)+(8*0)+(7*2)+(6*6)+(5*1)+(4*3)+(3*4)+(2*6)+(1*3)=103
103 % 10 = 3
So 1026134-63-3 is a valid CAS Registry Number.

1026134-63-3Upstream product

1026134-63-3Downstream Products

1026134-63-3Relevant academic research and scientific papers

AZAADAMANTANE DERIVATIVES AND METHODS OF USE

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Page/Page column 62; 97, (2008/12/06)

The invention relates to compounds that are azaadamantane derivatives, particularly ether- or amine-substituted azaadamantane derivatives and salts and prodrugs thereof, compositions comprising such compounds, methods of using such compounds and compositi

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