1026136-97-9Relevant academic research and scientific papers
Sequential ortho-lithiations; The sulfoxide group as a relay to enable meta-substitution
Flemming, Jonathan P.,Berry, Malcolm B.,Brown, John M.
, p. 1215 - 1221 (2008)
Sulfoxides are known to be powerful directing groups for ortho-lithiation, even in competition with other directors. This has been utilised to introduce substituents meta- to a methoxy-group by sequential lithiation, reaction with Me tert-butylsulfinate,
