10263-32-8

Upstream product

• 19641-29-3 6-chlorophthalide 

Downstream Products

• 1282510-17-1 (5-chloro-2-chloromethyl-phenyl)-(4-fluorophenyl)-methanone 
• 1282510-16-0 sodium {4-chloro-2-[(4-fluorophenyl)carbonyl]phenyl}methanesulfonate 
• 1282510-34-2 7-chloro-5-(4-fluoro-phenyl)-1,3-dihydro-2,3,4-benzothiadiazepin-2,2-dioxide 
• 1282510-39-7 7-chloro-5-(4-fluoro-phenyl)-3-methyl-1,3-dihydro-2,3,4-benzothiadiazepin-2,2-dioxide 

Relevant academic research and scientific papers

Chemistry of an Unexplored Heterocyclic Ring System: Versatile Synthesis of 5-Aryl-2,3,4-benzothiadiazepine 2,2-dioxides

The article gives insight into the synthetic approach of a practically new heterocyclic ring system, 2,3,4-benzothiadiazepines. Starting from the easily available phthalides, an efficient synthesis of 5-aryl-2,3,4-benzothiadiazepine 2,2-dioxides is described here. Owing to their close structural similarity to 2,3-benzodiazepines and 2,3-benzodiazepine-4-ones, two well-known bioactive compound families, the new derivatives can be of importance in medicinal chemistry.